Multiple allele problem: 3977 surveyed Swiss people were found with the following allele frequencies at the ABO blood groups: IA = 0.27 IB = 0.06 i = 0.67 calculate the genotype frequencies for the four blood types freq(IA IA): (0.27)(0.27) = 0.0729 freq(IA i): 2(0.27)(0.67) = 0.3618 freq(IB IB): (0.06)(0.06) = 0.0036 freq(IB i): 2(0.06)(0.67) = 0.0804 freq(IA IB): 2(0.27)(0.06) = 0.0324 freq(ii): (0.67)(0.67) = 0.4489 calculate the phenotype frequencies for the four blood types phenotype frequency of type A = 0.0729 + 0.3618 = 0.4347 phenotype frequency of type B = 0.0036 + 0.0804 = 0.0840 phenotype frequency of type AB = 0.0324 phenotype frequency of type O = 0.4489 calculate the numbers of individuals expected to have each genotype and phenotype if this population were in Hardy-Weinberg equilibrium. multiply the frequency by the number of people in the population: e.g., to calculate the numbers of individuals expected to have the genotype IA IA, multiply 0.0729 x 3977 = 290 to calculate the numbers of individuals expected to have the phenotype of type A blood, multiply 0.4347 x 3977 = 1729.