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Clinical Laboratory Science (CLS)
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Coleman, Paur (Program Director), Peterson, Porter, Schill and Sens (Chair)

http://www.med.und.nodak.edu/depts/cls

The University of North Dakota has offered a degree in clinical laboratory science since 1949. The Clinical Laboratory Science (CLS) program is accredited by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS), which is located at 8410 West Bryn Mawr, Suite 670, Chicago, IL 60631.


Clinical Laboratory Scientists, sometimes referred to as Medical Technologists, are key members of the health care team. They are concerned with the study and practice of diagnostic medicine and generate accurate and reliable test results in chemistry, hematology, immunology, immunohematology and microbiology. The results provide valuable information used in the diagnosis and treatment of disease. Excellent employment opportunities exist not only in hospitals and clinics, but also in physician offices, government agencies, industry, research, the armed forces and health related facilities. A severe shortage of clinical laboratory scientists exists and has generated a large demand for new graduates. In addition to immediate employment opportunities, many graduates attend medical school or pursue graduate degrees in science, management or education.


School of Medicine and Health Sciences

B.S. in Clinical Laboratory Science
The CLS degree includes two years of pre-professional (freshman and sophomore) education followed by two years of professional (junior and senior) coursework. Application for advancement to the professional education component is made during the second semester of the sophomore year. Applicants to the professional program must have a cumulative GPA of a least 2.8 and no more than one D in any math or science course. Exceptions for acceptance and continuance may be made by petition to the Department of Pathology Professional and Academic Standards Committee. During the second year of the professional curriculum (senior year), students register for courses in the summer, fall and spring semesters.

When a student is registered in 300 and 400 level CLS courses, a specific CLS tuition is assessed.


Required 130 credits (36 of which must be numbered 300 or above, and 60 credits of which must be from a four-year institution) including:
 
I.

General Education Requirements (see University GER listing).
 
II.

Curriculum:
   
Freshman Year
    FIRST SEMESTER
    Engl 110 College Composition I
(3)
    Bio 150 & 150L General Biology I and Laboratory
(4)
    Chem 121 & 121L General Chemistry I and Laboratory
(4)
    Math 103 or 104 College Algebra or Finite Math
(3)
   
SECOND SEMESTER
    Biol 151 General Biology II
(3)
    Comm 110 Fundamentals of Public Speaking
(3)
    Chem 122 & 122L General Chemistry II and Laboratory
(4)
    Engl 120 or 125 College Composition II or
      Technical and Business Writing
(3)
   
Sophomore Year
    FIRST SEMESTER
    MBio 202 Introductory Medical Microbiology Lecture
(3)
    Anat 204 Anatomy for Paramedical Personnel
(3)
    CLS 101 Orientation to Medical Laboratory Sciences
(2)
    Comm 212 Interpersonal Communications
(3)
    Social Science Introduction to Psychology (recommended)
(3)
    Humanities Elective (World Culture)
(3)
   
SECOND SEMESTER
    Chem 240 & 240L Survey of Organic Chemistry and Laboratory
(5)
    CLS 234 Human Parasitology
(2)
    CLS 234L Human Parasitology Lab
(1)
    CLS 238 Computer & Statistical Applications in CLS
(2)
    Social Science Principles of Microeconomics (recomended
(3)
    Humanities Elective  
(3)
   
Professional Curriculum Year 1
    Junior Year
    FIRST SEMESTER
    CLS 301 Immunology
(2)
    CLS 325 Hematology
(3)
    CLS 325L Hematology Laboratory
(2)
    CLS 336 Laboratory Calculations
(1)
    CLS 393 Immunohemotology/Immunology Laboratory
(2)
    PPT 301 Human Physiology
(4)
    Humanities Elective  
(3)
   
SECOND SEMESTER
    CLS 380 Professional Issues in CLS
(1)
    CLS 394 Medical Microbiology
(2)
    CLS 399 Spec. Topics: Molecular Diagnostics (recommended)
(2)
    CLS 399 Spec. Topics: Molecular Diag. Lab (recommended)
(1)
    BMB 301 Biochemistry
(3)
    BMB 303 Biochemistry Laboratory
(3)
    Mgmt 300 Prin. of Management
(3)
      OR
    Mgmt 305 Managerial Concepts
(3)
       
    Professional Curriculum Year 2
    Senior Year
    SUMMER SESSION
    CLS 470 Clinical Immunohematology I
(1)
    CLS 471 Clinical Chemistry Theory, Prin., Procedures,
      & Correlations
(2)
    CLS 472 Clinical Laboratory I
(1)
    CLS 473 Clinical Hemostasis
(2)
    CLS 474 Clinical Microscopy & Urinalysis
(2)
    CLS 477 Clinical Immunohematology Theory
(1)
    CLS 478 Clinical Microbiology Theory & Laboratory
(2)
    CLS 482 Clinical Hematology I
(2)
   
FIRST SEMESTER
    CLS 475 Clinical Body Fluides
(1)
    CLS 480 Clinical Immunohematology II
(2)
    CLS 481 Clinical Chemistry I
(3)
    CLS 483 Clinical Laboratory II
(1)
    CLS 484 Clinical Microbiology I
(2)
    CLS 485 Clinical Laboratory III
(1)
    CLS 486 Clinical Immunology
(1)
    CLS 487 Medical Mycology
(1)
   
SECOND SEMESTER
    CLS 490 Fin. & Qual. Management of the Cl. Laboratory
(3)
    CLS 491 Clinical Chemistry II
(1)
    CLS 492 Clinical Immunohematology III
(2)
    CLS 493 Clinical Hematology II
(3)
    CLS 495 Clinical Microbiology II
(2)
      Total Credits
130

4 + 1 Certification Program

The CLS program offers a 4 + 1 curriculum. A student is eligible for this program if they have earned a B.S. or B.A. degree and have completed the following prerequisite courses:
    General Chemistry
(8)
    Organic Chemistry
(3)
    Biochemistry
(3)
    General Biology
(6)
    Microbiology
(3)
    Anatomy
(3)
    Physiology
(3)
    CLS 234 Human Parasitology*
(2)
    CLS 301 Immunology*
(2)
    CLS 325 Hematology*
(3)
    CLS 325L Hematology Laboratory**
(2)
   

*  

Available online
** Offered as an intensive laboratory on campus in May.

Upon successful completion of the prerequisite coursework, the 4 + 1 student applies to the second year of the professional program. The applicant must have a cumulative GPA of a least 2.8, and no more than one D in any math or science course. Exceptions for acceptance and continuance may be made by petitioning the Department of Pathology Professional and Academic Standards Committee. When a student is registered in 300 and 400 level CLS courses, a specific CLS tuition is assessed.


Upon successful completion of the 4 + 1 program of study, the student will earn a B.S. in Clinical Laborary Science degree from UND and will be eligible to take a national certification examination and become a certified Clinical Laboratory Scientist and/or Medical Technologist.
    Professional Curriculum Year 2
    SUMMER SESSION
    CLS 470 Clinical Immunohematology I
(1)
    CLS 471 Clinical Chemistry, Theory, Principles., Procedures,
      & Correlations
(2)
    CLS 472 Clinical Laboratory I
(1)
    CLS 473 Clinical Hemostasis
(2)
    CLS 474 Clinical Microscopy & Urinalysis
(2)
    CLS 477 Clinical Immunohematology Theory
(1)
    CLS 478 Clinical Microbiology Theory & Laboratory
(2)
    CLS 482 Clinical Hematology I
(2)
   
FIRST SEMESTER
    CLS 475 Clinical Body Fluids
(1)
    CLS 480 Clinical Immunohematology II
(2)
    CLS 481 Clinical Chemistry I
(3)
    CLS 483 Clinical Laboratory II
(1)
    CLS 484 Clinical Microbiology I
(2)
    CLS 485 Clinical Laboratory III
(1)
    CLS 486 Clinical Immunology
(1)
    CLS 487 Medical Mycology
(1)
   
SECOND SEMESTER
    CLS 490 Fin. & Qual. Management of the Cl. Laboratory
(3)
    CLS 491 Clinical Chemistry II
(1)
    CLS 492 Clinical Immunohematology III
(2)
    CLS 493 Clinical Hematology II
(3)
    CLS 495 Clinical Microbiology II
(2)

Articulation Program


Clinical Laboratory Technician (CLT) or Medical Laboratory Technician (MLT) graduates are encouraged to apply to the UND CLS program. A CLT/MLT graduate will be eligible for the transfer of up to 60 semester credits depending on the curriculum completed. Transfer credits allow the waiver of several science courses in the professional curriculum. The student’s record is evaluated and a recommendation made to the Registrar regarding the number of credits to be transferred and the science courses to be waived. The student may be eligible for a shortened professional program based on previous coursework, years of experience working in a clinical laboratory, and a competency assessment. A specific outline for the number of credits that will transfer has been incorporated into articulation agreements with numerous regional technical and community colleges. Contact the CLS program for additional information.

When a student is registered in 300 and 400 level CLS courses, a specific CLS tuition is assessed.


Western College Alliance for Clinical Laboratory Science (WCACLS) Education

The Clinical Laboratory Science program is affiliated with Bemidji State University, Bemidji, MN; Jamestown College, Jamestown, ND; Minot State University, Minot, ND; Montana State University, Bozeman, MT; University of Mary, Bismarck, ND; and the University of Montana, Missoula, MT. The program of study for the first three years at these colleges is aligned with the UND CLS program. Students from these institutions apply to the UND CLS program for their final year of study. Upon completion they receive a certificate from the University of North Dakota verifying completion of 12 months of clinical training in the UND NAACLS accredited program. They are then eligible for a degree in Clinical Laboratory Science or a related major from their respective institution.

B.S. Degree, 4+1 Certificate, and WCACLS Students (Professional Curriculum Year 2)

The Clinical Laboratory Science program is affiliated with Bemidji State University, Bemidji, MN; Jamestown College, Jamestown, ND; Minot State University, Minot, ND; Montana State University, Billings and Bozeman, MT; South Dakota State University, Brookings, SD; University of Mary, Bismarck, ND; University of Montana, Missoula, MT; University of South Dakota, Vermillion, SD; University of Wisconsin-La Crosse; and Winona State University, Winona, MN. The program of study for the first three years at these colleges is aligned with the UND CLS program. Students from these institutions apply to the UND CLS program for their final year of study. Upon completion they receive a certificate from the University of North Dakota verifying completion of 12 months of clinical training in the UND NAACLS accredited program. They are then eligible for a degree in Clinical Laboratory Science or a related major from their respective institution and eligible to complete a national certification exam.

B.S. Degree, 4+1, and WCACLS Students
(Professional Curriculum Year 2)


A summer practicum experience on the UND campus in Grand Forks, ND is required, followed by approximately seven months in a clinical laboratory of a medical center. There are special requirements prior to contact with patients and testing of patient specimens. A background check and specific antibody titers are required by all clinical affiliates prior to work with patients. Students are responsible for additional costs that include: travel, housing, food, and summer lab course fees during the second year of the professional curriculum.

The program has clinical affiliation agreements with over 40 medical centers in North Dakota, Minnesota, Montana, Colo- rado and Oregon for the clinical experience. A complete list and description of the current clinical sites is available at http://medicine.nodak.edu/cls.

The CLS program reserves the right to place on probation or to cancel the registration of any student whose performance in the classroom or clinical experience is unsatisfactory.

Program accommodations for qualified handicapped persons will be reviewed upon notification of a prospective student’s needs and limitations.



CLS Categorical Training (Certificate) Program


The CLS Categorical Training (Certificate) program provides advanced skills to baccalaureate prepared students to become eligible to work in a high complexity clinical laboratory and meet the requirements to take a national certification examination in a specific categorical area.

The requirements for entrance include a baccalaureate degree from an accredited college or university and completion of 36 semester hours in biology, chemistry and/or medical sciences (in addition to or part of the baccalaureate degree). It includes four “category” choices: Immunohematology, Chemistry/Urinalysis, Microbiology, or Hematology. The curriculum includes both an academic and a clinical component. When a student is registered in 300 and 400 level CLS courses, a specific CLS tuition is assessed. The curriculum for each categorical is as follows:


  CLINICAL CHEMISTRY/URINALYSIS
  CLS 336 Laboratory Calculations
1
  CLS 460 Laboratory Practice Theory
4
  CLS 461 Laboratory Practice Application
1
  CLS 471 Clinical Chemistry Theory, Principles,
    Procedures & Correl
2
  CLS 474 Clinical Microscopy and Urinalysis
2
  CLS 475 Clinical Body Fluids
1
  CLS 481 Clinical Chemistry I
3
  CLS 485 Clinical Laboratory II
1
  CLS 491 Clinical Chemistry III
2
  Total Categorical Credits
17*


HEMATOLOGY/HEMOSTASIS
 
  CLS 325 Hematology
3
  CLS 325L Hematology Laboratory
2
  CLS 336 Laboratory Calculations
1
  CLS 460 Laboratory Practice Theory
4
  CLS 461 Laboratory Practice Application
1
  CLS 473 Clinical Hemostasis
2
  CLS 482 Clinical Hematology I
2
  CLS 493 Clinical Hematology II
3
  Total Categorical Credits
18*


IMMUNOHEMATOLOGY
 
  CLS 301 Immunology
2
  CLS 336 Laboratory Calculations
1
  CLS 460 Laboratory Practice Theory
4
  CLS 461 Laboratory Practice Application
1
  CLS 393 Immunoehmatology/Immunology Lab
2
  CLS 470 Clinical Immunohematology I
1
  CLS 477 Clinical Immunohematology Theory
1
  CLS 480 Clinical Immunohematology II
2
  CLS 492 Clinical Immunohematology III
2
  Total Categorical Credits
16*
 
MICROBIOLOGY
  CLS 234 Parasitology
2
  CLS 336 Laboratory Calculations
1
  CLS 394 Medical Microbiology (recommended
2
  CLS 460 Laboratory Practice Theory
4
  CLS 461 Laboratory Practice Application
1
  CLS 478 Medical Microbiology Theory and Laboratory
2
  CLS 484 Clinical Immunohematology II
2
  CLS 487 Clinical Mycology
2
  CLS 495 Clinical Microbiology
2
  TOTAL
16*
 
* Eligible for Categorical National Certification Exam
 

Online Courses

There are many courses offered by the CLS program through online or distance learning. The primary method of distance learning course delivery is WEB based. Students participating in online coursework are required to have Internet access. Specific computer requirements are available from the CLS program.

Graduate Level Programs

A Master of Science (M.S.) degree with a major in CLS and a certificate program in CLS Management is available. The graduate level programs are described in the graduate section of this catalog and at http://www.medicine.nodak.edu/cls.

Courses


The Clinical Laboratory Science program is part of the Division of Medical Laboratory Sciences in the Department of Pathology. The Clinical Laboratory Science (CLS) courses that are offered are listed below.

101. Orientation to Medical Laboratory Sciences. 2 credits. Introduction to the role, ethics, conduct, certification, education, employment, and fundamental knowledge and skills related to medical laboratory science. F

234. Human Parasitology. 2 credits. Physiological aspects of human parasites, their symbiotic host parasite relationships and clinical diagnostic techniques. S

234L. Human Parsitology Laboratory. 1 credit. Laboratory methods for the identification and diagnosis of human parasites. S

238. Computer and Statistical Application in Clinical Laboratory Science. 2 credits. Clinical applications of modern information systems, terminology, word processing, data base, spread sheet and statistical analysis including normal and binomial distribution, t-tests, chi square tests, analysis of variance, linear regression and correlation. S

301. Immunology. 2 credits. Principles of clinical immunology focusing on the cellular and molecular nature of antigens and immunoglobulin, the immune response, immunogenetics, and immune mediated disease. S

325. Hematology. 3 credits. Identification of normal and abnormal blood cells in various hematological disorders. Theory and application of hematology procedures. Theory and mechanisms of hemostasis. F

325L. Hematology Laboratory. 2 credits. Corequisite: CLS 325. Morphologic examination of blood and bone marrow and laboratory testing used in hematological study. F

336. Laboratory Calculations. 1 credit. Calculations used in the clinical laboratory including measurement systems, dilutions, graphing, solution chemistry, statistics of quality control and research interpretation. F

360. Histopathology Laboratory Theory. 3 credits. This course presents an overview of standard histopathology laboratory calculations, safety, quality assurance, information management, laboratory education, instrumentation, and proper specimen collection and handling.

361. Histology Laboratory Technique. 1 credit. Techniques and practice in use of general laboratory equipment, reagents and procedures utilized in histology.

362. Histotechniques I. 3 credits. This course is the introduction to the fundamental techniques, including fixation, processing, instrumentation, and solution preparation. Cytoplasmic, nuclear, carbohydrate, and amyloid staining will be presented.

363. Histotechniques II. 3 credits. This course is the continuation of the fundamental techniques of histology including muscle and connective tissue, nerves, microorganisms, pigment, minerals, Cytoplasmic granules, immunohistochemistry, and enzyme histochemistry.

367. Histology Practicum I. 3 credits. Communication skills, attitude and work performance will be evaluated. The skills involved will emphasize the fundamental techniques including fixation, specimen processing, instrumentation, sectioning and staining with emphasis on the Hematoxylin and Eosin stain.

368. Histology Practicum II. 3 credits. Individual assignments in an accredited histology lab. Emphasis on refining skills learned in Histology Practicum I, staining procedures and tissue identification.

380. Professional Issues in Clinical Laboratory Science. 1 credit. Discussion of CLS professional issues, ethics, current topics of healthcare delivery, governmental regulations, societal concerns, cultural diversity, disease prevention, research and environment. SS

393. Immunohematology/Immunology Laboratory. 2 credits. Corequisite: CLS 301. Theory and practical application of laboratory investigations of immunology serology, and immunohematology. S

394. Medical Microbiology. 2 credits. Medically important microorganisms are identified using a wide variety of clinical techniques. Included in the discussion will be susceptibility studies and the correlation of the presence of microorganisms to health and disease. S

399. Special Topics in Clinical Laboratory Science. 1-13 credits. Lecture, discussion, and readings on topics of current interest in the clinical laboratory sciences. F, S, SS

430. Clinical Practicum I.
13 credits. Applied theory and practice at the clinical affiliate. F

440. Clinical Practicum II. 12 credits. Techniques and practice in the clinical affiliate. S

460. Laboratory Practice Theory. 4 credits. This course represents an overview of standard laboratory practices including safety, management of service and quality, information management and laboratory education, instrumentation and equipment, research and specimen collection and handling. F,S,SS

461. Laboratory Practice Application. 1 credit. Techniques and practice in use of general laboratory equipment, reagents and procedures. F,S,SS

470. Clinical Immunohematology I. 1 credit. Practical application of modern transfusion techniques, component therapy, and quality assurance. SS

471. Clinical Chemistry Theory, Principles, Procedures, and Correlations. 2 credits. Theories and principles of clinical chemistry procedures are discussed as well as how the results of these procedures correlate to health and disease. SS

472. Clinical Laboratory I. 1 credit. Theory and practice of phlebotomy in the clinical setting, specimen processing, review of state and federal regulations, safety and biohazard compliance, interpersonal relationship skills. SS

473. Clinical Hemostasis. 2 credits. Physiologic mechanisms of normal human hemostasis as well as hereditary and acquired defects. Laboratory techniques performed and discussed are screening tests and specific assays for abnormalities, procedures to monitor therapeutic measures and practice and maintenance of current instrumentation. SS

474. Clinical Microscopy & Urinalysis.
2 credits. Theory, techniques and practice of microscopy and urinalysis with emphasis on identification of elements in the sediment. SS

475. Clinical Body Fluids. 1 credit. Overview of the theory and practice in manual procedures of human body fluids. The body fluids to be discussed include: spinal, synovial and amniotic fluid, transudates and exudates, fecal specimens, gastric, sweat, and other body fluid secretions. F

477. Clinical Immunohematology Theory.
1 credit. Theory of modern transfusion techniques, component therapy, and quality assurance. SS

478. Clinical Microbiology Theory and Laboratory.
2 credits. Groups of medically important bacteria are studied and correlated to laboratory practice in identification. Included in the discussions are antibiotic susceptibility testing, quality control, and methods of identification including rapid, automated, and traditional methods. SS

480. Clinical Immunohematology II. 2 credits. Applied theory and modern transfusion at the clinical affiliate. Annually.

481. Clinical Chemistry I. 3 credits. Applied theory and practice in clinical chemistry at the clinical affiliate. F

482. Clinical Hematology I.
2 credits. Emphasis on interpretive correlation of hematology findings and pathophysiology. Topics of current interest and advances in hematology. SS

483. Clinical Laboratory II. 1 credit. Techniques and practice in routine phlebotomy at the clinical affiliate. Annually.

484. Clinical Microbiology I. 2 credits. Applied theory and practice in clinical microbiology at the clinical affiliate. F

485. Clinical Laboratory III. 1 credit. Observation, practice, or research in specialized areas or settings at the clinical affiliate. F